Determine which of the anthropometric or plasma biochemical parameters best describes the relative size of intra-abdominal fat in relatively healthy adults.
Obesity is one of the most frequent and faster growing problem in the world. Obesity is associated with an increased risk of developing cardiovascular diseases (CVD) and diabetes mellitus type 2 (DMT2). Intra-abdominal adipose tissue is more closely associated with CVD and DMT2 development. It is important to consider early detection and type of the obesity, as well as capabilities to reduce obesity. There is a need for cheap and non-invasive methodology for the determination of obesity in GP practice.
The distribution of TAF in Th10-L2 level for women- 72% are SCF and only 28%> IAF. While for men only 45% of the TAF are SCF and 55% - IAF. WC statistically (p<0.005) correlated with SCF (rw=0.89), IAF (rw=0.85) and TAF (rw=0.92) in women group, while in men WC statistically correlated with the SCF (rm=0.82), IAF (rm=0.82) and TAF (rm=0.85). BMI statistically correlated in both (women and men) with SCF (rw=0.91; rm=0.78), IAF (rw=0.75; rm=0.80) and TAF (rw=0.90; rm=0.83). From biochemical parameters only TG had statistically significant correlation with the IAF (rw=0.57; rm=0.69) and TAF (rw=0.42; rm=0.65), both men and women, but there was no significant correlation with the SCF in both groups.
60 relatively healthy persons (30 women); age 37.4 ± 4.1 years. Anthropometric measurements as waist circumference (WC) and body mass index (BMI), blood tests- total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides (TG) were taken from all patients. Every patient had abdominal computed tomography in which we examined fat distribution (total abdominal fat (TAF), sub-cutaneous fat (SCF) and intra-abdominal fat (IAF) in TH10-L2 level. The abdominal fat segment volumes were compared with anthropometric and biochemical parameters.
Total abdominal fat level for men and women do not differ significantly, however, there was a significant difference in fat distribution. The level of the IAF for both, women and men, best describes the TG serum concentrations. Overweight and obese patients should always measure TG levels in GP practice to indicate a greater risk to develop CVD and DMT2.